MyHelse™️ offers employers a comprehensive solution for employee wellness and supporting employees in achieving their health and fitness goals. https://myhelse.com/
2024 Trend Updates: What Really Works In SEO & Content MarketingSearch Engine Journal
21 slides•638.9K views
The future of SEO is trending toward a more human-first and user-centric approach, powered by AI intelligence and collaboration. Are you ready?
Watch as we explore which SEO trends to prioritize to achieve sustainable growth and deliver reliable results. We’ll dive into best practices to adapt your strategy around industry-wide disruptions like SGE, how to navigate the top challenges SEO professionals are facing, and proven tactics for prioritizing quality and building trust.
You’ll hear:
- The top SEO trends to prioritize in 2024 to achieve long-term success.
- Predictions for SGE’s impact, and how to adapt.
- What E-E-A-T really means, and how to implement it holistically (hint: it’s never been more important).
With Zack Kadish and Alex Carchietta, we’ll show you which SEO trends to ignore and which to focus on, along with the solution to overcoming rapid, significant and disruptive Google algorithm updates.
If you’re looking to cut through the noise of constant SEO and content trends to drive success, you won’t want to miss this webinar.
Storytelling For The Web: Integrate Storytelling in your Design ProcessChiara Aliotta
39 slides•522.8K views
In this slides I explain how I have used storytelling techniques to elevate websites and brands and create memorable user experiences. You can discover practical tips as I showcase the elements of good storytelling and its applied to some examples of diverse brands/projects..
This presentation by Thibault Schrepel, Associate Professor of Law at Vrije Universiteit Amsterdam University, was made during the discussion “Artificial Intelligence, Data and Competition” held at the 143rd meeting of the OECD Competition Committee on 12 June 2024. More papers and presentations on the topic can be found at oe.cd/aicomp.
This presentation was uploaded with the author’s consent.
How to Leverage AI to Boost Employee Wellness - Lydia Di Francesco - SocialHR...SocialHRCamp
28 slides•160.8K views
Speaker: Lydia Di Francesco
In this workshop, participants will delve into the realm of AI and its profound potential to revolutionize employee wellness initiatives. From stress management to fostering work-life harmony, AI offers a myriad of innovative tools and strategies that can significantly enhance the wellbeing of employees in any organization. Attendees will learn how to effectively leverage AI technologies to cultivate a healthier, happier, and more productive workforce. Whether it's utilizing AI-powered chatbots for mental health support, implementing data analytics to identify internal, systemic risk factors, or deploying personalized wellness apps, this workshop will equip participants with actionable insights and best practices to harness the power of AI for boosting employee wellness. Join us and discover how AI can be a strategic partner towards a culture of wellbeing and resilience in the workplace.
2024 State of Marketing Report – by HubspotMarius Sescu
43 slides•120.9K views
https://www.hubspot.com/state-of-marketing
· Scaling relationships and proving ROI
· Social media is the place for search, sales, and service
· Authentic influencer partnerships fuel brand growth
· The strongest connections happen via call, click, chat, and camera.
· Time saved with AI leads to more creative work
· Seeking: A single source of truth
· TLDR; Get on social, try AI, and align your systems.
· More human marketing, powered by robots
ChatGPT is a revolutionary addition to the world since its introduction in 2022. A big shift in the sector of information gathering and processing happened because of this chatbot. What is the story of ChatGPT? How is the bot responding to prompts and generating contents? Swipe through these slides prepared by Expeed Software, a web development company regarding the development and technical intricacies of ChatGPT!
Product Design Trends in 2024 | Teenage EngineeringsPixeldarts
8 slides•52K views
The realm of product design is a constantly changing environment where technology and style intersect. Every year introduces fresh challenges and exciting trends that mold the future of this captivating art form. In this piece, we delve into the significant trends set to influence the look and functionality of product design in the year 2024.
How Race, Age and Gender Shape Attitudes Towards Mental HealthThinkNow
21 slides•37.7K views
Mental health has been in the news quite a bit lately. Dozens of U.S. states are currently suing Meta for contributing to the youth mental health crisis by inserting addictive features into their products, while the U.S. Surgeon General is touring the nation to bring awareness to the growing epidemic of loneliness and isolation. The country has endured periods of low national morale, such as in the 1970s when high inflation and the energy crisis worsened public sentiment following the Vietnam War. The current mood, however, feels different. Gallup recently reported that national mental health is at an all-time low, with few bright spots to lift spirits.
To better understand how Americans are feeling and their attitudes towards mental health in general, ThinkNow conducted a nationally representative quantitative survey of 1,500 respondents and found some interesting differences among ethnic, age and gender groups.
Technology
For example, 52% agree that technology and social media have a negative impact on mental health, but when broken out by race, 61% of Whites felt technology had a negative effect, and only 48% of Hispanics thought it did.
While technology has helped us keep in touch with friends and family in faraway places, it appears to have degraded our ability to connect in person. Staying connected online is a double-edged sword since the same news feed that brings us pictures of the grandkids and fluffy kittens also feeds us news about the wars in Israel and Ukraine, the dysfunction in Washington, the latest mass shooting and the climate crisis.
Hispanics may have a built-in defense against the isolation technology breeds, owing to their large, multigenerational households, strong social support systems, and tendency to use social media to stay connected with relatives abroad.
Age and Gender
When asked how individuals rate their mental health, men rate it higher than women by 11 percentage points, and Baby Boomers rank it highest at 83%, saying it’s good or excellent vs. 57% of Gen Z saying the same.
Gen Z spends the most amount of time on social media, so the notion that social media negatively affects mental health appears to be correlated. Unfortunately, Gen Z is also the generation that’s least comfortable discussing mental health concerns with healthcare professionals. Only 40% of them state they’re comfortable discussing their issues with a professional compared to 60% of Millennials and 65% of Boomers.
Race Affects Attitudes
As seen in previous research conducted by ThinkNow, Asian Americans lag other groups when it comes to awareness of mental health issues. Twenty-four percent of Asian Americans believe that having a mental health issue is a sign of weakness compared to the 16% average for all groups. Asians are also considerably less likely to be aware of mental health services in their communities (42% vs. 55%) and most likely to seek out information on social media (51% vs. 35%).
Adulterants screening in Herbal products using Modern Analytical Techniques28SamruddhiKadam
21 slides•382 views
Basic introduction to adulteration in Herbal products, M Pharm Pharmaceutical Analysis Semester 2
Basic types of Adulterations in herbal products.
Modern hyphenated techniques used in determination of adulteration of herbal drugs which includes TLC, HPTLC, HPLC, LC-MS, LC-NMR, SFC, LC-IR,etc.
Various modern analytical techniques used in Quantification of Adulterants present in herbal product.
Examples of various drugs causing adulteration in Herbal products.
The uterus is a hollow, muscular organ located in the female pelvis between the bladder and the rectum. It's a key structure in the female reproductive system and plays a central role in menstruation, pregnancy, and labor.
Parts of the Uterus:
Fundus: The top, dome-shaped portion above the openings of the fallopian tubes.
Body (Corpus): The central, main part where implantation of a fertilized egg occurs.
Isthmus: The narrow region between the body and cervix.
Cervix: The lower, narrow part that opens into the vagina. It produces mucus and dilates during childbirth.
Layers of the Uterine Wall:
Endometrium: The inner lining that thickens during the menstrual cycle and sheds during menstruation if pregnancy doesn’t occur.
Myometrium: The thick, muscular middle layer responsible for contractions during menstruation and labor.
Perimetrium: The outer serous layer that covers the uterus.
2025-04-09 ICPM_Amsterdam_Alain van Gool.pdfAlain van Gool
40 slides•110 views
Lecture for a groep of senior pharmaceutical professionals on the potential and pitfalls of digital biomarkers and continuous monitoring, with forward views to pharmaceutical development.
tailored academic roadmaps, mentored 50+ students through licensure exam prep...Dawit Alemu
293 slides•14 views
Pharmacology is a critical discipline within the field of public health, as it encompasses the study of drugs and their effects on the human body. In the context of a Master of Public Health (MPH) program, understanding pharmacology is essential for addressing issues related to drug use, therapy, and the management of diseases at the population level. It aids in making informed decisions about pharmaceutical interventions, optimizing drug therapies, and improving public health outcomes.Pharmacology in MPH involves exploring the mechanisms of action, therapeutic uses, side effects, and safety profiles of various drugs. It also includes examining the distribution, metabolism, and excretion of drugs within different populations, particularly vulnerable groups like children, the elderly, or those with pre-existing health conditions. A sound knowledge of pharmacology enables public health professionals to design evidence-based programs, manage drug-related risks, and ensure access to effective and safe medications.
The integration of pharmacological knowledge into public health practice can support efforts in areas such as disease prevention, health promotion, and the management of chronic conditions, infectious diseases, and drug resistance. MPH students with a pharmacological foundation are equipped to contribute to drug policy development, health system management, and the development of educational campaigns aimed at promoting safe medication use and addressing public health challenges related to pharmacology.
Anti malarial agents of pharmacology by Darade K.Kkrushna darade
16 slides•143 views
The PDF titled “Anti Malarial Agents” provides a detailed overview of malaria, its causative Plasmodium species, life cycle, symptoms, and the classification of antimalarial drugs. It explains drug mechanisms, pharmacokinetics, adverse effects, and therapeutic uses, aiding in understanding malaria treatment and prevention.
Unlocking the Secrets of the Skeletal System: Relevance for NursingViresh Mahajani
104 slides•1.2K views
This presentation provides nursing students with a comprehensive understanding of the skeletal system, crucial for effective patient care. We will explore the anatomy and physiology of bones, joints, and cartilage, emphasizing their vital roles in support, movement, and protection. Key topics include common skeletal disorders, their clinical manifestations, and the nurse's role in assessment, intervention, and patient education. This session aims to equip future nurses with the foundational knowledge necessary to address musculoskeletal health issues and promote optimal patient outcomes across diverse healthcare settings.
PREMATURE RUPTURE OF MEMBRANES.pptx FOR NURSING STUDENTS CREATED BY KIRAN KAR...KIRAN KARETHA
34 slides•192 views
Premature rupture of membranes (PROM), also known as pre-labor rupture of membranes, refers to the rupture of the amniotic sac (or "water breaking") before the onset of true labor.
TYPES
Preterm premature rupture of membrane: when rupture of membranes occurs before the 37th week of gestational age.
Term premature rupture of membrane: when rupture of membranes occurs at or after the 37th week of pregnancy but before the onset of true labor.
3) Prolonged premature rupture of membrane: when rupture of membranes occurs for more than 24 hours before delivery.
4) Pre-viable pre-term premature rupture of membrane: when rupture of membranes occurs before 24 weeks of gestation. It is also known as Mid-trimester premature rupture of membrane
CLINICAL MANIFESTATION
painless leakage of fluid from vagina
fetal can easily feel through belly due to loss of fluid
decrease uterine size
abdominal pain and back pain
fetal heart sound altered
gush of fluid
oligohydramnios
DIAGNOSTIC EVALUATION
History collection (steady loss of small amount of fluid from vagina)
Sterile speculum examination: A sterile speculum examination involves using a sterile speculum, a medical instrument, to gently open the vagina for a visual examination of the cervix and vaginal walls, ensuring the speculum is sterilized before use, to prevent infection.
Pooling test: During a speculum examination, healthcare providers look for amniotic fluid accumulating in the posterior vaginal fornix (the area at the back of the vagina).
This pooling of fluid suggests that the amniotic sac has ruptured, allowing fluid to leak into the vagina.
Nitrazine test: The nitrazine test, using nitrazine paper (phenaphthazine), is a method to determine vaginal pH and detect potential amniotic fluid leakage, which can indicate a ruptured amniotic membrane, by observing a color change from yellow to blue.
Fern test: The fern test involves collecting a vaginal fluid sample, allowing it to dry on a glass slide, and then examining the dried sample under a microscope.
When amniotic fluid is present, the sodium chloride in it crystallizes, forming a characteristic fern-like pattern.
MANAGEMENT
If the patient is term > 37 weeks : Approximately 90% of patient will go into spontaneous labor within 24 hours. labor should be induced either at the time of presentation or the patient can be expected managed.
Induction of labor reduces the time of delivery and the rates of chorioamnionitis and endometritis and admission to the neonatal intensive care unit.
If the patient does not go into spontaneous labor on her own then labor induction should be performed with oxytocin. So, use oxytocin or prostaglandins as indicated Otherwise, perform cesarean delivery.
COMPLICATIONS
IF FETUS REMAIN IN UTERO
Neonatal conditions
Infection and sepsis
Deformations
Umbilical cord compression
Pulmonary hypoplasia
Learning Objectives:
1. Define action potential
Illustrate different phases of action potential and explain ionic & electrical changes occurring during each phase of action potential
2. Differentiate between myelinated and nonmyelinated nerve fibers based on their structure and characteristics
3. Describe the conduction of action potential in unmyelinated and myelinated neurons
4. Explain the concept of saltatory conduction
5. Differentiate between action potential and local potential
Overview of Parkinson’s disease :- Etiology, types, pathogenesis,signs,treate...Arghadeep Sarkar
20 slides•30 views
This ppt consisting about Parkinsonism and parkinson's disease and all related points like etiology,types of PD, pathogenesis,epidemology,signs -syptoms, diagnosis, treatment, drug classification
PEPTIC ULCER DISEASE (PUD) , H PYLORI AND GERD TREATMENT BY DR .ANKUSH GOYAL ...Dr Ankush goyal
43 slides•185 views
Comprehensive Management of Peptic Ulcer Disease and GERD
I. Introduction
Peptic Ulcer Disease (PUD) and Gastroesophageal Reflux Disease (GERD) are distinct yet overlapping disorders of the gastrointestinal system, marked by significant morbidity worldwide. These conditions illustrate the consequence of a disturbed harmony between offensive gastric secretions and the protective barriers of the mucosa. From ancient remedies to modern-day proton pump inhibitors and eradication therapies, the treatment approaches to these disorders represent a triumph of translational medicine.
While PUD typically involves mucosal erosion in the stomach or proximal duodenum due to Helicobacter pylori infection or NSAID use, GERD arises from the reflux of gastric contents into the esophagus due to incompetent lower esophageal sphincter tone. Both conditions necessitate a thorough understanding of their etiopathogenesis for rational therapy and long-term management. This document explores the latest, evidence-based treatment paradigms, structured with clarity and clinical relevance.
---
II. Peptic Ulcer Disease (PUD)
Definition and Epidemiology
Peptic ulcers are breaks in the mucosal lining of the stomach or duodenum that penetrate the muscularis mucosa. Gastric ulcers typically occur on the lesser curvature of the stomach, while duodenal ulcers are found in the first part of the duodenum.
Globally, the prevalence of PUD has declined, largely due to H. pylori eradication, yet NSAID-related ulcers persist, especially among the elderly.
Etiology and Risk Factors
Helicobacter pylori infection – Present in ~90% of duodenal and 70% of gastric ulcers.
NSAIDs – Inhibit prostaglandin synthesis, compromising mucosal defense.
Smoking – Impairs mucosal healing.
Stress (critical illness) – Leads to stress ulcers.
Zollinger-Ellison Syndrome – Gastrinoma with excess acid secretion.
Corticosteroids, alcohol, and genetic predisposition are other contributors.
Pathophysiology
The balance between aggressive factors (acid, pepsin, H. pylori, NSAIDs) and defensive mechanisms (mucus, bicarbonate, blood flow, prostaglandins) determines mucosal integrity.
H. pylori causes chronic inflammation and epithelial damage. NSAIDs decrease prostaglandins, reducing mucosal blood flow and bicarbonate production.
---
III. Clinical Features of Peptic Ulcer
Epigastric pain: Most common symptom; burning or gnawing in nature.
Duodenal ulcers: Pain relieved by food, occurs 2–3 hours after meals.
Gastric ulcers: Pain worsens with food intake.
Nausea, bloating, early satiety
Complications:
Bleeding: Hematemesis, melena.
Perforation: Sudden severe abdominal pain.
Gastric outlet obstruction
Penetration into adjacent organs (e.g., pancreas)
---
IV. Diagnosis of Peptic Ulcer
Endoscopy: Gold standard for diagnosis and biopsy to rule out malignancy.
Rapid urease test, histology, urea breath test, stool antigen – for H. pylori.
Serologic testing (less preferred).
Barium study
AI Trends in Creative Operations 2024 by Artwork Flow.pdfmarketingartwork
29 slides•68.8K views
Creative operations teams expect increased AI use in 2024. Currently, over half of tasks are not AI-enabled, but this is expected to decrease in the coming year. ChatGPT is the most popular AI tool currently. Business leaders are more actively exploring AI benefits than individual contributors. Most respondents do not believe AI will impact workforce size in 2024. However, some inhibitions still exist around AI accuracy and lack of understanding. Creatives primarily want to use AI to save time on mundane tasks and boost productivity.
Organizational culture includes values, norms, systems, symbols, language, assumptions, beliefs, and habits that influence employee behaviors and how people interpret those behaviors. It is important because culture can help or hinder a company's success. Some key aspects of Netflix's culture that help it achieve results include hiring smartly so every position has stars, focusing on attitude over just aptitude, and having a strict policy against peacocks, whiners, and jerks.
Adulterants screening in Herbal products using Modern Analytical Techniques28SamruddhiKadam
21 slides•382 views
Basic introduction to adulteration in Herbal products, M Pharm Pharmaceutical Analysis Semester 2
Basic types of Adulterations in herbal products.
Modern hyphenated techniques used in determination of adulteration of herbal drugs which includes TLC, HPTLC, HPLC, LC-MS, LC-NMR, SFC, LC-IR,etc.
Various modern analytical techniques used in Quantification of Adulterants present in herbal product.
Examples of various drugs causing adulteration in Herbal products.
The uterus is a hollow, muscular organ located in the female pelvis between the bladder and the rectum. It's a key structure in the female reproductive system and plays a central role in menstruation, pregnancy, and labor.
Parts of the Uterus:
Fundus: The top, dome-shaped portion above the openings of the fallopian tubes.
Body (Corpus): The central, main part where implantation of a fertilized egg occurs.
Isthmus: The narrow region between the body and cervix.
Cervix: The lower, narrow part that opens into the vagina. It produces mucus and dilates during childbirth.
Layers of the Uterine Wall:
Endometrium: The inner lining that thickens during the menstrual cycle and sheds during menstruation if pregnancy doesn’t occur.
Myometrium: The thick, muscular middle layer responsible for contractions during menstruation and labor.
Perimetrium: The outer serous layer that covers the uterus.
2025-04-09 ICPM_Amsterdam_Alain van Gool.pdfAlain van Gool
40 slides•110 views
Lecture for a groep of senior pharmaceutical professionals on the potential and pitfalls of digital biomarkers and continuous monitoring, with forward views to pharmaceutical development.
tailored academic roadmaps, mentored 50+ students through licensure exam prep...Dawit Alemu
293 slides•14 views
Pharmacology is a critical discipline within the field of public health, as it encompasses the study of drugs and their effects on the human body. In the context of a Master of Public Health (MPH) program, understanding pharmacology is essential for addressing issues related to drug use, therapy, and the management of diseases at the population level. It aids in making informed decisions about pharmaceutical interventions, optimizing drug therapies, and improving public health outcomes.Pharmacology in MPH involves exploring the mechanisms of action, therapeutic uses, side effects, and safety profiles of various drugs. It also includes examining the distribution, metabolism, and excretion of drugs within different populations, particularly vulnerable groups like children, the elderly, or those with pre-existing health conditions. A sound knowledge of pharmacology enables public health professionals to design evidence-based programs, manage drug-related risks, and ensure access to effective and safe medications.
The integration of pharmacological knowledge into public health practice can support efforts in areas such as disease prevention, health promotion, and the management of chronic conditions, infectious diseases, and drug resistance. MPH students with a pharmacological foundation are equipped to contribute to drug policy development, health system management, and the development of educational campaigns aimed at promoting safe medication use and addressing public health challenges related to pharmacology.
Anti malarial agents of pharmacology by Darade K.Kkrushna darade
16 slides•143 views
The PDF titled “Anti Malarial Agents” provides a detailed overview of malaria, its causative Plasmodium species, life cycle, symptoms, and the classification of antimalarial drugs. It explains drug mechanisms, pharmacokinetics, adverse effects, and therapeutic uses, aiding in understanding malaria treatment and prevention.
Unlocking the Secrets of the Skeletal System: Relevance for NursingViresh Mahajani
104 slides•1.2K views
This presentation provides nursing students with a comprehensive understanding of the skeletal system, crucial for effective patient care. We will explore the anatomy and physiology of bones, joints, and cartilage, emphasizing their vital roles in support, movement, and protection. Key topics include common skeletal disorders, their clinical manifestations, and the nurse's role in assessment, intervention, and patient education. This session aims to equip future nurses with the foundational knowledge necessary to address musculoskeletal health issues and promote optimal patient outcomes across diverse healthcare settings.
PREMATURE RUPTURE OF MEMBRANES.pptx FOR NURSING STUDENTS CREATED BY KIRAN KAR...KIRAN KARETHA
34 slides•192 views
Premature rupture of membranes (PROM), also known as pre-labor rupture of membranes, refers to the rupture of the amniotic sac (or "water breaking") before the onset of true labor.
TYPES
Preterm premature rupture of membrane: when rupture of membranes occurs before the 37th week of gestational age.
Term premature rupture of membrane: when rupture of membranes occurs at or after the 37th week of pregnancy but before the onset of true labor.
3) Prolonged premature rupture of membrane: when rupture of membranes occurs for more than 24 hours before delivery.
4) Pre-viable pre-term premature rupture of membrane: when rupture of membranes occurs before 24 weeks of gestation. It is also known as Mid-trimester premature rupture of membrane
CLINICAL MANIFESTATION
painless leakage of fluid from vagina
fetal can easily feel through belly due to loss of fluid
decrease uterine size
abdominal pain and back pain
fetal heart sound altered
gush of fluid
oligohydramnios
DIAGNOSTIC EVALUATION
History collection (steady loss of small amount of fluid from vagina)
Sterile speculum examination: A sterile speculum examination involves using a sterile speculum, a medical instrument, to gently open the vagina for a visual examination of the cervix and vaginal walls, ensuring the speculum is sterilized before use, to prevent infection.
Pooling test: During a speculum examination, healthcare providers look for amniotic fluid accumulating in the posterior vaginal fornix (the area at the back of the vagina).
This pooling of fluid suggests that the amniotic sac has ruptured, allowing fluid to leak into the vagina.
Nitrazine test: The nitrazine test, using nitrazine paper (phenaphthazine), is a method to determine vaginal pH and detect potential amniotic fluid leakage, which can indicate a ruptured amniotic membrane, by observing a color change from yellow to blue.
Fern test: The fern test involves collecting a vaginal fluid sample, allowing it to dry on a glass slide, and then examining the dried sample under a microscope.
When amniotic fluid is present, the sodium chloride in it crystallizes, forming a characteristic fern-like pattern.
MANAGEMENT
If the patient is term > 37 weeks : Approximately 90% of patient will go into spontaneous labor within 24 hours. labor should be induced either at the time of presentation or the patient can be expected managed.
Induction of labor reduces the time of delivery and the rates of chorioamnionitis and endometritis and admission to the neonatal intensive care unit.
If the patient does not go into spontaneous labor on her own then labor induction should be performed with oxytocin. So, use oxytocin or prostaglandins as indicated Otherwise, perform cesarean delivery.
COMPLICATIONS
IF FETUS REMAIN IN UTERO
Neonatal conditions
Infection and sepsis
Deformations
Umbilical cord compression
Pulmonary hypoplasia
Learning Objectives:
1. Define action potential
Illustrate different phases of action potential and explain ionic & electrical changes occurring during each phase of action potential
2. Differentiate between myelinated and nonmyelinated nerve fibers based on their structure and characteristics
3. Describe the conduction of action potential in unmyelinated and myelinated neurons
4. Explain the concept of saltatory conduction
5. Differentiate between action potential and local potential
Overview of Parkinson’s disease :- Etiology, types, pathogenesis,signs,treate...Arghadeep Sarkar
20 slides•30 views
This ppt consisting about Parkinsonism and parkinson's disease and all related points like etiology,types of PD, pathogenesis,epidemology,signs -syptoms, diagnosis, treatment, drug classification
PEPTIC ULCER DISEASE (PUD) , H PYLORI AND GERD TREATMENT BY DR .ANKUSH GOYAL ...Dr Ankush goyal
43 slides•185 views
Comprehensive Management of Peptic Ulcer Disease and GERD
I. Introduction
Peptic Ulcer Disease (PUD) and Gastroesophageal Reflux Disease (GERD) are distinct yet overlapping disorders of the gastrointestinal system, marked by significant morbidity worldwide. These conditions illustrate the consequence of a disturbed harmony between offensive gastric secretions and the protective barriers of the mucosa. From ancient remedies to modern-day proton pump inhibitors and eradication therapies, the treatment approaches to these disorders represent a triumph of translational medicine.
While PUD typically involves mucosal erosion in the stomach or proximal duodenum due to Helicobacter pylori infection or NSAID use, GERD arises from the reflux of gastric contents into the esophagus due to incompetent lower esophageal sphincter tone. Both conditions necessitate a thorough understanding of their etiopathogenesis for rational therapy and long-term management. This document explores the latest, evidence-based treatment paradigms, structured with clarity and clinical relevance.
---
II. Peptic Ulcer Disease (PUD)
Definition and Epidemiology
Peptic ulcers are breaks in the mucosal lining of the stomach or duodenum that penetrate the muscularis mucosa. Gastric ulcers typically occur on the lesser curvature of the stomach, while duodenal ulcers are found in the first part of the duodenum.
Globally, the prevalence of PUD has declined, largely due to H. pylori eradication, yet NSAID-related ulcers persist, especially among the elderly.
Etiology and Risk Factors
Helicobacter pylori infection – Present in ~90% of duodenal and 70% of gastric ulcers.
NSAIDs – Inhibit prostaglandin synthesis, compromising mucosal defense.
Smoking – Impairs mucosal healing.
Stress (critical illness) – Leads to stress ulcers.
Zollinger-Ellison Syndrome – Gastrinoma with excess acid secretion.
Corticosteroids, alcohol, and genetic predisposition are other contributors.
Pathophysiology
The balance between aggressive factors (acid, pepsin, H. pylori, NSAIDs) and defensive mechanisms (mucus, bicarbonate, blood flow, prostaglandins) determines mucosal integrity.
H. pylori causes chronic inflammation and epithelial damage. NSAIDs decrease prostaglandins, reducing mucosal blood flow and bicarbonate production.
---
III. Clinical Features of Peptic Ulcer
Epigastric pain: Most common symptom; burning or gnawing in nature.
Duodenal ulcers: Pain relieved by food, occurs 2–3 hours after meals.
Gastric ulcers: Pain worsens with food intake.
Nausea, bloating, early satiety
Complications:
Bleeding: Hematemesis, melena.
Perforation: Sudden severe abdominal pain.
Gastric outlet obstruction
Penetration into adjacent organs (e.g., pancreas)
---
IV. Diagnosis of Peptic Ulcer
Endoscopy: Gold standard for diagnosis and biopsy to rule out malignancy.
Rapid urease test, histology, urea breath test, stool antigen – for H. pylori.
Serologic testing (less preferred).
Barium study
AI Trends in Creative Operations 2024 by Artwork Flow.pdfmarketingartwork
29 slides•68.8K views
Creative operations teams expect increased AI use in 2024. Currently, over half of tasks are not AI-enabled, but this is expected to decrease in the coming year. ChatGPT is the most popular AI tool currently. Business leaders are more actively exploring AI benefits than individual contributors. Most respondents do not believe AI will impact workforce size in 2024. However, some inhibitions still exist around AI accuracy and lack of understanding. Creatives primarily want to use AI to save time on mundane tasks and boost productivity.
Organizational culture includes values, norms, systems, symbols, language, assumptions, beliefs, and habits that influence employee behaviors and how people interpret those behaviors. It is important because culture can help or hinder a company's success. Some key aspects of Netflix's culture that help it achieve results include hiring smartly so every position has stars, focusing on attitude over just aptitude, and having a strict policy against peacocks, whiners, and jerks.
PEPSICO Presentation to CAGNY Conference Feb 2024Neil Kimberley
39 slides•36.7K views
PepsiCo provided a safe harbor statement noting that any forward-looking statements are based on currently available information and are subject to risks and uncertainties. It also provided information on non-GAAP measures and directing readers to its website for disclosure and reconciliation. The document then discussed PepsiCo's business overview, including that it is a global beverage and convenient food company with iconic brands, $91 billion in net revenue in 2023, and nearly $14 billion in core operating profit. It operates through a divisional structure with a focus on local consumers.
Content Methodology: A Best Practices Report (Webinar)contently
50 slides•19.2K views
This document provides an overview of content methodology best practices. It defines content methodology as establishing objectives, KPIs, and a culture of continuous learning and iteration. An effective methodology focuses on connecting with audiences, creating optimal content, and optimizing processes. It also discusses why a methodology is needed due to the competitive landscape, proliferation of channels, and opportunities for improvement. Components of an effective methodology include defining objectives and KPIs, audience analysis, identifying opportunities, and evaluating resources. The document concludes with recommendations around creating a content plan, testing and optimizing content over 90 days.
How to Prepare For a Successful Job Search for 2024Albert Qian
37 slides•41.2K views
The document provides guidance on preparing a job search for 2024. It discusses the state of the job market, focusing on growth in AI and healthcare but also continued layoffs. It recommends figuring out what you want to do by researching interests and skills, then conducting informational interviews. The job search should involve building a personal brand on LinkedIn, actively applying to jobs, tailoring resumes and interviews, maintaining job hunting as a habit, and continuing self-improvement. Once hired, the document advises setting new goals and keeping skills and networking active in case of future opportunities.
A report by thenetworkone and Kurio.
The contributing experts and agencies are (in an alphabetical order): Sylwia Rytel, Social Media Supervisor, 180heartbeats + JUNG v MATT (PL), Sharlene Jenner, Vice President - Director of Engagement Strategy, Abelson Taylor (USA), Alex Casanovas, Digital Director, Atrevia (ES), Dora Beilin, Senior Social Strategist, Barrett Hoffher (USA), Min Seo, Campaign Director, Brand New Agency (KR), Deshé M. Gully, Associate Strategist, Day One Agency (USA), Francesca Trevisan, Strategist, Different (IT), Trevor Crossman, CX and Digital Transformation Director; Olivia Hussey, Strategic Planner; Simi Srinarula, Social Media Manager, The Hallway (AUS), James Hebbert, Managing Director, Hylink (CN / UK), Mundy Álvarez, Planning Director; Pedro Rojas, Social Media Manager; Pancho González, CCO, Inbrax (CH), Oana Oprea, Head of Digital Planning, Jam Session Agency (RO), Amy Bottrill, Social Account Director, Launch (UK), Gaby Arriaga, Founder, Leonardo1452 (MX), Shantesh S Row, Creative Director, Liwa (UAE), Rajesh Mehta, Chief Strategy Officer; Dhruv Gaur, Digital Planning Lead; Leonie Mergulhao, Account Supervisor - Social Media & PR, Medulla (IN), Aurelija Plioplytė, Head of Digital & Social, Not Perfect (LI), Daiana Khaidargaliyeva, Account Manager, Osaka Labs (UK / USA), Stefanie Söhnchen, Vice President Digital, PIABO Communications (DE), Elisabeth Winiartati, Managing Consultant, Head of Global Integrated Communications; Lydia Aprina, Account Manager, Integrated Marketing and Communications; Nita Prabowo, Account Manager, Integrated Marketing and Communications; Okhi, Web Developer, PNTR Group (ID), Kei Obusan, Insights Director; Daffi Ranandi, Insights Manager, Radarr (SG), Gautam Reghunath, Co-founder & CEO, Talented (IN), Donagh Humphreys, Head of Social and Digital Innovation, THINKHOUSE (IRE), Sarah Yim, Strategy Director, Zulu Alpha Kilo (CA).
Trends In Paid Search: Navigating The Digital Landscape In 2024Search Engine Journal
31 slides•20.4K views
The search marketing landscape is evolving rapidly with new technologies, and professionals, like you, rely on innovative paid search strategies to meet changing demands.
It’s important that you’re ready to implement new strategies in 2024.
Check this out and learn the top trends in paid search advertising that are expected to gain traction, so you can drive higher ROI more efficiently in 2024.
You’ll learn:
- The latest trends in AI and automation, and what this means for an evolving paid search ecosystem.
- New developments in privacy and data regulation.
- Emerging ad formats that are expected to make an impact next year.
Watch Sreekant Lanka from iQuanti and Irina Klein from OneMain Financial as they dive into the future of paid search and explore the trends, strategies, and technologies that will shape the search marketing landscape.
If you’re looking to assess your paid search strategy and design an industry-aligned plan for 2024, then this webinar is for you.
5 Public speaking tips from TED - Visualized summarySpeakerHub
16 slides•18.9K views
From their humble beginnings in 1984, TED has grown into the world’s most powerful amplifier for speakers and thought-leaders to share their ideas. They have over 2,400 filmed talks (not including the 30,000+ TEDx videos) freely available online, and have hosted over 17,500 events around the world.
With over one billion views in a year, it’s no wonder that so many speakers are looking to TED for ideas on how to share their message more effectively.
The article “5 Public-Speaking Tips TED Gives Its Speakers”, by Carmine Gallo for Forbes, gives speakers five practical ways to connect with their audience, and effectively share their ideas on stage.
Whether you are gearing up to get on a TED stage yourself, or just want to master the skills that so many of their speakers possess, these tips and quotes from Chris Anderson, the TED Talks Curator, will encourage you to make the most impactful impression on your audience.
See the full article and more summaries like this on SpeakerHub here: https://speakerhub.com/blog/5-presentation-tips-ted-gives-its-speakers
See the original article on Forbes here:
http://www.forbes.com/forbes/welcome/?toURL=http://www.forbes.com/sites/carminegallo/2016/05/06/5-public-speaking-tips-ted-gives-its-speakers/&refURL=&referrer=#5c07a8221d9b
ChatGPT and the Future of Work - Clark Boyd Clark Boyd
69 slides•67.3K views
Everyone is in agreement that ChatGPT (and other generative AI tools) will shape the future of work. Yet there is little consensus on exactly how, when, and to what extent this technology will change our world.
Businesses that extract maximum value from ChatGPT will use it as a collaborative tool for everything from brainstorming to technical maintenance.
For individuals, now is the time to pinpoint the skills the future professional will need to thrive in the AI age.
Check out this presentation to understand what ChatGPT is, how it will shape the future of work, and how you can prepare to take advantage.
The document provides career advice for getting into the tech field, including:
- Doing projects and internships in college to build a portfolio.
- Learning about different roles and technologies through industry research.
- Contributing to open source projects to build experience and network.
- Developing a personal brand through a website and social media presence.
- Networking through events, communities, and finding a mentor.
- Practicing interviews through mock interviews and whiteboarding coding questions.
Google's Just Not That Into You: Understanding Core Updates & Search IntentLily Ray
99 slides•18.8K views
1. Core updates from Google periodically change how its algorithms assess and rank websites and pages. This can impact rankings through shifts in user intent, site quality issues being caught up to, world events influencing queries, and overhauls to search like the E-A-T framework.
2. There are many possible user intents beyond just transactional, navigational and informational. Identifying intent shifts is important during core updates. Sites may need to optimize for new intents through different content types and sections.
3. Responding effectively to core updates requires analyzing "before and after" data to understand changes, identifying new intents or page types, and ensuring content matches appropriate intents across video, images, knowledge graphs and more.
A brief introduction to DataScience with explaining of the concepts, algorithms, machine learning, supervised and unsupervised learning, clustering, statistics, data preprocessing, real-world applications etc.
It's part of a Data Science Corner Campaign where I will be discussing the fundamentals of DataScience, AIML, Statistics etc.
Time Management & Productivity - Best PracticesVit Horky
42 slides•176.9K views
Here's my presentation on by proven best practices how to manage your work time effectively and how to improve your productivity. It includes practical tips and how to use tools such as Slack, Google Apps, Hubspot, Google Calendar, Gmail and others.
The six step guide to practical project managementMindGenius
27 slides•41.7K views
The six step guide to practical project management
If you think managing projects is too difficult, think again.
We’ve stripped back project management processes to the
basics – to make it quicker and easier, without sacrificing
the vital ingredients for success.
“If you’re looking for some real-world guidance, then The Six Step Guide to Practical Project Management will help.”
Dr Andrew Makar, Tactical Project Management
Unlocking the Power of ChatGPT and AI in Testing - A Real-World Look, present...Applitools
138 slides•60.1K views
During this webinar, Anand Bagmar demonstrates how AI tools such as ChatGPT can be applied to various stages of the software development life cycle (SDLC) using an eCommerce application case study. Find the on-demand recording and more info at https://applitools.info/b59
Key takeaways:
• Learn how to use ChatGPT to add AI power to your testing and test automation
• Understand the limitations of the technology and where human expertise is crucial
• Gain insight into different AI-based tools
• Adopt AI-based tools to stay relevant and optimize work for developers and testers
* ChatGPT and OpenAI belong to OpenAI, L.L.C.
The document discusses various AI tools from OpenAI like GPT-3 and DALL-E 2, as well as ChatGPT. It explores how search engines are using AI and things to consider around AI-generated content. Potential SEO uses of ChatGPT are also presented, such as generating content at scale, conducting topic research, and automating basic coding tasks. The document encourages further reading on using ChatGPT for SEO purposes.
More than Just Lines on a Map: Best Practices for U.S Bike Routes
This session highlights best practices and lessons learned for U.S. Bike Route System designation, as well as how and why these routes should be integrated into bicycle planning at the local and regional level.
Presenters:
Presenter: Kevin Luecke Toole Design Group
Co-Presenter: Virginia Sullivan Adventure Cycling Association
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